Cover
Vol. 9 No. 1 (2019)

Published: November 30, 2019

Pages: 32-51

Research Article

Clinical Role of Follicle Stimulating Hormone, Luteinizing Hormone and Testosterone as Predictive Markers of Sperm Yield by Testicular Biopsy in Azoospermic Patients

Hussain Kh. Kadhem 1 Hayder A. L. Mossa 2 Ula M.R. Al-Kawaz 1
1Dyala Health Directorate, Al Batool Teaching Hospital, Department of Infertility, Dyala, Iraq
2High Institute of Infertility Diagnosis and Assisted Reproductive Technologies, Al Nahrain University, Baghdad, Iraq
History
  • Received: May 16, 2019
  • Accepted: November 3, 2019
  • Available Online: November 15, 2019
DOI

https://doi.org/10.28969/IJEIR.v9.i1.r3

Abstract

The study aim is to evaluate the predictive rate of positive sperm retrieval of serum concentration of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone (TT) in azoospermic patients presenting to High Institute of infertility diagnosis and assisted reproductive technologies. The study records of 65 azoospermic men with who underwent open testicular sperm extraction between February 2017 to April 2019 were studied. The patient’s age, hormonal profile for FSH, LH and TT and testicular histopathology were recorded. The sperm retrieval rate according to histological findings norm-spermatogenesis (NS), hypo-spermatogenesis (HS), maturation arrest (MA) and Sertoli cell-only syndrome (SCOS) were recorded as follows: 100%, 75%, 44.4%, and 28.6% respectively. The cutoff value of FSH was (≤ 14.56 mIU/L) with an accuracy level of 73.0%, a sensitivity (66.7 %) and a specificity (79.3 %). The cutoff value of the serum level of LH was (≤ 9.37 mIU/L) with an accuracy level of 78.4%, a sensitivity level of 77.7 % and a specificity level of 72.4 %.

Keywords

References

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  27. Meijerink AM, Cissen M, Mochtar MH, Fleischer K, Thoonen I, de Melker AA, Meissner A, Repping S, Braat DDM, van Wely M, Ramos L. Prediction model for live birth in ICSI using testicular extracted sperm. Human Reproduction. Oxford University Press (OUP); 2016;31(9):1942–51. Doi: http://dx.doi.org/10.1093/humrep /dew146 [ResearchGate] [Oxford] Biography Dr. Hussain Kaleefa Kadhem He received MBChB in medicine and general surgery from Baghdad College of Medicine, University of Baghdad, Iraq in 1993. The Higher Diploma in General Surgery from Tikrit University in 2002. The M.Sc. in Infertility and Assisted Reproductive Technique from the High Institute of infertility diagnosis and ART, Al-Nahrain University in 2012. The Ph.D. in Infertility and Clinical Reproduction, from the High Institute of infertility diagnosis and ART, Al-Nahrain University in 2019. He has the Part-A MRCS, Royal College of Surgeon of England. A Diploma from WALS in Laparoscopic surgery India, in 2008. He is a member of the world association of laparoscopic surgery, Iraqi fertility association, Iraqi Association of Surgery. Dr. Hayder A. L. Mossa He is an assistant professor at Al Nahrain University. He is a member of the Iraqi Society of Fertility, Iraqi Society of Zoonotic Diseases (ISZD) & Iraqi Zoonotic Communicable Diseases (ISZCD), Iraqi Academics Syndicate, European Society of Human Reproduction and Embryology (ESHRE). An editorial board member of Merit Research Journal of Medicine and Medical Sciences (MRJMMS), International Journal of Medical Research & Health Sciences (IJMRHS). A reviewer at global journals Inc. (USA). He was a candidate for the award of Arabian Young Researchers in 2007. He granted for many appreciation certificates in the scientific & administrative fields. He participated & supervised in more than 60 scientific & medical conferences, workshops & training course. Has many kinds of research & articles published in Iraqi & national medical journals. Chief & member of nearly 60 scientific & administrative committees from 2006-till now. Has interests in assisted reproductive technologies, reproductive micromanipulation, medical terminology, research methods and seminars, reproductive physiology, advanced embryology. Dr. Ula M. R. Al-Kawaz He is a Professor of Urology at Al-Nahrain University. Currently, he is the dean of the high institute of infertility diagnosis and ARTs, Al- Nahrain University. He is a fellow of the Iraqi Board for Medical Specialization, Council of Urology since 2006, and a fellow of the European Board of Urology, since 2009. He published more than 27 articles both local and international. He supervised many M.Sc. and Ph.D. students. How to cite: Kadhem HK, Mossa HAL, Al-Kawaz UMR. Clinical Role of Follicle Stimulating Hormone, Luteinizing Hormone and Testosterone as Predictive Markers of Sperm Yield by Testicular Biopsy in Azoospermic Patients; Iraqi Journal of Embryos and Infertility Researches (IJEIR), (2019);9(1):32-51. Doi: http://doi.org/10.28969/IJEIR.v9.i1.r3 © 2019 Author(s)