Cover
Vol. 14 No. 2 (2024)

Published: December 31, 2024

Pages: 1-16

Research Article

The Association of Age and Body Mass Index with Salivary Stress Biomarkers(Alpha-amylase and Cortisol) in Infertile Men: A Cross-Sectional Study

Layla Kadhum Radeef 1 Ali Ibrahim Rahim 2 Ula Al-Kawaz
1High Institute of Infertility Diagnosis and Assisted Reproductive Technologies, Al Nahrain University, Baghdad, Iraq.
2College of Medicine / University of Al-Ameed/Al-Kafeel IVF Center, Karbala, Iraq.
History
  • Received: October 7, 2024
  • Accepted: October 30, 2024
  • Available Online: December 8, 2024
DOI

https://doi.org/10.28969/IJEIR.v14.i2.r7.24

Abstract

The purpose of the study was to determine if age and body mass index in infertile men were associated with stress levels as determined by salivary stress biomarkers (cortisol and alpha-amylase). A cross-sectional study comprising 100 males with an infertility challenge was divided into 25 normozoospermia, 26 oligozoospermia, 21 asthenozoospermia, and 28 oligoasthenoteratozoospermia. Salivary cortisol and alpha-amylase were examined using the ELISA technique . The average age of the patient was 30.85±7.03, and their average BMI was 27.604±5. 7894. The infertile duration mean was 4.7896±3. 85932. The average amylase content in the saliva was 127.3721±40.0952, while the average cortisol content was 72.67±49.09. There are no discernible variations between the comparison mean of BMI and the duration of infertility. In the current investigation, there was no discernible relationship between SAA and age, BMI, or the length of infertility. Saliva cortisol and BMI in the oligoasthenoteratozoospermia group showed a substantial negative correlation (r = 0.483 & p = 0.009), although no significant link was seen with age, BMI, or length of infertility in the other study groups. There was no significant positive or negative correlation found between SAA level and the age and BMI of the four study groups, whereas salivary cortisol showed a substantial negative correlation with BMI in OAT and a non-significant correlation with age.

Keywords

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