Cover
Vol. 13 No. 2 (2023)

Published: November 30, 2023

Pages: 16-25

Research Article

The correlation of intratesticular testosterone with body mass index and smoking.

Sara Hamdi Salih 1 Ali Ibrahim Rahim 2 Ula Al-Kawaz
1High Institute of Infertility Diagnosis and Assisted Reproductive Technologies, Al Nahrain University, Baghdad, Iraq.
2College of Medicine, Al-Ameed University ,
History
  • Received: October 7, 2023
  • Accepted: October 30, 2023
  • Available Online: November 8, 2023
DOI

https://doi.org/10.28969/IJEIR.v13.i2.r2.23

Abstract

Intratesticular testosterone plays a crucial role in male reproductive function and overall health. Body Mass Index (BMI) and smoking are known lifestyle factors that can influence hormonal balances. Elevated BMI has been associated with alterations in testosterone levels, impacting male fertility and endocrine function. The aim was to examine the concurrent relationships between intratesticular testosterone, BMI, and smoking habits. Biopsies of the testicles were taken from 32 patients with non-obstructive azoospermia. Testicular sperm extraction (TESE) under spinal or general anesthesia was performed after a comprehensive history, physical examination, and investigations. After performing a minced biopsy and centrifuging the fluid, testicular fluid was extracted. The highest intratesticular testosterone levels were in normal patients and lowest levels in over weight patient; on the contrary the highest serum 17-hydroxyprogesterone levels were found in over weight patient and lowest levels in normal weight patients; There were insignificantly higher both intratesticular testosterone and 17-hydroxyprogesterone levels in non-smokers. In conclusion, the statistical analysis revealed that there is an insignificantly low correlation between intratesticular testosterone levels, BMI, and smoking.

Keywords

References

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